catalog number :
MBS173090
products full name :
Glutamate Pyruvate Transaminase (GPT), Alanine Transaminase (ALT)
products short name :
Alanine Aminotransferase
products name syn :
Glutamate Pyruvate Transaminase; Alanine Transaminase; serum glutamic-pyruvic transaminase; SGPT; GPT; ALT; ALAT; Alanine Aminotransferase (ALT, GPT), Porcine Heart - Lyophilized
other names :
Alanine aminotransferase 1; Alanine aminotransferase 1; Glutamate pyruvate transaminase 1; GPT 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1
products gene name syn :
AAT1; GPT1
other gene names :
GPT; AAT1; GPT1; ALT1; GPT 1
uniprot entry name :
ALAT1_PIG
specificity :
Liver damage or disease
form :
Lyophilized from tris-chloride buffer, pH 7.0 with sodium chloride, EDTA, DTT, alpha-ketoglurarte, and pyridoxal-5-phosphate
storage stability :
Aliquot and freeze at -20 degree C after reconstitution.
other info1 :
Appearance: Yellow to yellow-green powder. EC Number: 2.6.1.2. Unit Definition: One unit will catalyze the transamination of one micromole per minute of L-alanine to a-ketoglutarate, forming L-glutamate and pyruvate, at 37 degree C and pH 7.4. Specific Activity: 90 U/mg protein (A280). 180 U/mg protein (Coomasie). Solubility: Clear, yellow-green solution (1mg/ml saline)
other info2 :
Reconstitution: Clear, yellow-green in 10 mg/mL saline. Recertification: 6-17-2018. Protein: 0.99 mg protein/mg (A280/Q0030). 0.50 mg protein/mg (Coomassie/Q0030). Contaminants: CPK: 0.05%, GLDH: <0.01%, AST/SGOT: <0.1%, LDH: <0.01%, Protease: < 0.01 U/mg (<0.001 OD/8 minutes). Ammonia: <0.01 micromole/mg. CAS Number: 9000-86-6. Activity: 90 U/mg (Dimension Clinical Chemistry System). Storage Note: Protect from moisture. Handling: Handle as a potentially hazardous substance.
products categories :
Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Alanine Aminotransferase (alt; Gpt)
products description :
MyBioSource is the leading producer of Porcine Heart Glutamic-Pyruvate Transaminase (GPT) enzyme, also known as Alanine transaminase (ALT) and alanine aminotransferase for research and clinical diagnostic assays for liver disease. Custom preparations, technical support, bulk quantities and aliquoting available. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers around the world. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. GPT/ALT test is often ordered in conjunction with aspartate aminotransferase (AST) or as part of a liver panel to screen for and/or help diagnose liver disease. AST and ALT are considered to be two of the most important tests to detect liver injury, although ALT is more specific than AST. Sometimes AST is compared directly to ALT and an AST/ALT ratio is calculated. This ratio may be used to distinguish between different causes of liver damage. GPT values are often compared to the results of other tests such as alkaline phosphatase (ALP), total protein, and bilirubin to help determine which form of liver disease is present. ALT is often used to monitor the treatment of persons who have liver disease, to see if the treatment is working, and may be ordered either by itself or along with other tests for this purpose.
ncbi mol weight :
~80,000