Glutamate Oxaloacetate Transaminase (GOT); Aspartate Transferase (AST), Porcine Heart | MyBioSource MBS173081 product information

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product summary

company name :

MyBioSource

product type :

protein

product name :

Glutamate Oxaloacetate Transaminase (GOT); Aspartate Transferase (AST), Porcine Heart

catalog :

MBS173081

quantity :

20000 Units

price :

225 USD

product information

catalog number :

MBS173081

products type :

Protein

products full name :

Glutamate Oxaloacetate Transaminase (GOT); Aspartate Transferase (AST), Porcine Heart

products short name :

Aspartate Aminotransferase

products name syn :

Aspartate Transaminase; Glutamate Oxaloacetate; AST; GOT; sGOT; AspAT; ASAT; AAT; serum glutamic oxaloacetic transaminase; Aspartate Aminotransferase (AST, GOT), Porcine Heart - Ammonium Sulfate

other names :

glutamate oxaloacetate transaminase; Aspartate aminotransferase, cytoplasmic; aspartate aminotransferase, cytoplasmic; transaminase A; aspartate transaminase 1; aspartate aminotransferase 1; growth-inhibiting protein 18; cysteine transaminase, cytoplasmic; glutamate oxaloacetate transaminase 1; cysteine aminotransferase, cytoplasmic; glutamic-oxaloacetic transaminase 1, soluble; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cCAT; Glutamate oxaloacetate transaminase 1; Transaminase A

products gene name :

GOT1

other gene names :

GOT1; GOT1; cCAT; GIG18; cAspAT; ASTQTL1; cAspAT; cCAT

uniprot entry name :

AATC_PIG

sequence length :

413

purity :

Purified

form :

Liquid. Appearance: Yellow/green suspension

storage stability :

2-8 degree C

other info1 :

Source: Porcine Heart. EC Number: 2.6.1.1. Unit Definition: One unit will catalyze the transamination of one micromole of L-aspartate to alpha-ketoglutarate forming L-glutamate and oxaloacetate per minute at 37 degree C and pH 7.8. Specific Activity: Reported U/mg protein

other info2 :

Recertification: 1 year. Protein: >= 5.0 mg protein/mL (Coomassie). Contaminants: CPK: <=0.1%, GPT/ALT: <=0.1%, LDH: <=0.01%, gGT: <=0.01%, ALP: <=0.01%. CAS Number: 9000-97-9. Activity: 1,500 - 2,500 U/mL (Dimension Clinical Chemistry System)

products categories :

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Aspartate Aminotransferase (ast; Got)

products description :

MyBioSource manufactures porcine heart Glutamate Oxaloacetate Transaminase (GOT)/Asparate Transferase (AST) for research, life science and manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. The blood test for aspartate aminotransferase is usually used to detect liver damage. It is often ordered in conjunction with another liver enzyme, alanine aminotransferase, or as part of a liver panel to screen for and/or help diagnose liver disorders. They are considered to be two of the most important tests to detect liver injury, although ALT is more specific than AST. Sometimes AST is compared directly to ALT and an AST/ALT ratio is calculated. This ratio may be used to distinguish between different causes of liver damage.

ncbi gi num :

3452380

ncbi acc num :

AAC32851.1

uniprot acc num :

P00503

ncbi mol weight :

~92,000

ncbi summary :

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008]

uniprot summary :

GOT1: Plays a key role in amino acid metabolism. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Protein type: EC 2.6.1.1; EC 2.6.1.3; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - arginine and proline; Transferase; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - cysteine and methionine. Chromosomal Location of Human Ortholog: 10q24.1-q25.1. Cellular Component: lysosome; cytoplasm; nerve terminal; cytosol; nucleus. Molecular Function: cysteine transaminase activity; carboxylic acid binding; phosphatidylserine decarboxylase activity; aspartate transaminase activity; pyridoxal phosphate binding. Biological Process: glutamate metabolic process; oxaloacetate metabolic process; glutamate catabolic process to aspartate; response to glucocorticoid stimulus; aspartate biosynthetic process; glucose metabolic process; pathogenesis; gluconeogenesis; 2-oxoglutarate metabolic process; methionine salvage; cellular response to insulin stimulus; glycerol biosynthetic process; sulfur amino acid metabolic process; fatty acid homeostasis; carbohydrate metabolic process; aspartate catabolic process; aspartate metabolic process; amino acid biosynthetic process; glutamate catabolic process to 2-oxoglutarate; polyamine metabolic process. Disease: Aspartate Aminotransferase, Serum Level Of, Quantitative Trait Locus 1

size1 :

20000 Units

price1 :

225 USD

size2 :

50000 Units

price2 :

360

size3 :

250000 Units

price3 :

1235