protein

Creatine Kinase MM Isoenzyme

MBS173060

1000 Units

490 USD

Protein

Creatine Kinase MM Isoenzyme

[Creatine Kinase MM]

[CK-MM; CKMM]

[creatine kinase M-type; Creatine kinase M-type; creatine kinase M-type; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CKCreatine kinase M-type, N-terminally processed]

[CKM]

[CKMM]

[CKM; CKM; CKMM; M-CK; CKMM]

KCRM_HUMAN

381

>= 96% (SDS-PAGE)

Appearance: White powder. Powdered lyophilized from tris chloride with DTT and EDTA, pH 7.5

Reconstitute with tris buffered saline containing 1 mM DTT and 1% BSA. Store up to 24 hours at 2-8 degree C or up to three months at -20 degree C. Avoid freeze-thaw cycles.

Source: Human Skeletal Muscle. Unit Definition: One unit will catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37 degree C.

Solubility: Clear,colorless (1 mg/mL saline). Protein: >= 0.84 mg protein/mg solid (Coomassie). Contaminants: LDH: 0.01%. GOT: = 99% CKMM (Helena QuickGel CK). Activity: 630 U/mg solid. Specific Activity: 750 U/mg protein. Ammonia: <0.1 micromole/mg

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Creatine Kinase Mm (ck-mm)

MyBioSource is the leading supplier of human Creatine Kinase MM (CK-MM) Isoenzyme for medical research and diagnostic manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Human CK-MM isoenzyme also known as human CPK-3 isoenzyme is normally responsible for almost all human CPK enzyme activity in healthy people. When human (CK-MM) CKMM isoenzyme is elevated, this usually indicates injury or stress to skeletal muscle.

21536288

NP_001815.2

NM_001824.4

86,000

Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Creatine Metabolism Pathway (106192); Creatine Pathway (413359); Creatine Pathway (468234); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Regulation Of Retinoblastoma Protein Pathway (137916); Urea Cycle And Metabolism Of Amino Groups Pathway (198758)

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. Protein type: Amino Acid Metabolism - arginine and proline; EC 2.7.3.2; Kinase, other. Chromosomal Location of Human Ortholog: 19q13.32. Cellular Component: cytosol. Molecular Function: creatine kinase activity; ATP binding. Biological Process: phosphocreatine biosynthetic process; phosphorylation; creatine metabolic process

1000 Units

490 USD