Catalase, Bovine Liver - >10,000 U/mg protein | MyBioSource MBS173044 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Catalase, Bovine Liver - >10,000 U/mg protein

catalog :

MBS173044

quantity :

100 mg

price :

130 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS173044

products type :

Protein

products full name :

Catalase, Bovine Liver - >10,000 U/mg protein

products short name :

Catalase

products name syn :

H2O2 oxidoreductase; Catalase, Bovine - Lyophilized, >10,000 U/mg protein

other names :

catalase; Catalase; catalase; catalase

products gene name :

H2O2

other gene names :

CAT; CAT

uniprot entry name :

CATA_HUMAN

sequence length :

527

purity :

Purified

form :

Lyophilized. Appearance: Green powder

storage stability :

At -20 degree C

other info1 :

Source: Bovine Liver. EC Number: 1.11.1.6. Unit Definition: One unit will catalyze the conversion of one micromole of hydrogen peroxide to oxygen and water per minute at 25 degree C and pH 7.0.

other info2 :

Recertification: 3 years. Protein: >= 0.5 mg protein/mg (Coomassie). Contaminants: AST/GOT: 7,500 U/mg powder

products categories :

Proteins; Enzymes; Standards/controls; Native Proteins; Catalase

products description :

MyBioSource produces bulk quantities of Bovine Liver Catalase for laboratory uses, research and diagnostic manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Catalase is an enzyme found in the blood and in most living cells that catalyzes the decomposition of hydrogen peroxide into water and oxygen. It has one of the highest turnover rates for all enzymes; one molecule of catalase can convert millions of molecules of hydrogen peroxide to water and oxygen per second. In microbiology, the catalase test is used to differentiate between bacterial species in the lab.

ncbi gi num :

4557014

ncbi acc num :

NP_001743.1

ncbi gb acc num :

NM_001752.3

ncbi mol weight :

59,756 Da

ncbi pathways :

Amyotrophic Lateral Sclerosis (ALS) Pathway (920975); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Cellular Responses To Stress Pathway (645258); DNA Damage Response (only ATM Dependent) Pathway (198827); Detoxification Of Reactive Oxygen Species Pathway (1127552); Folate Metabolism Pathway (198833); FoxO Family Signaling Pathway (138036); FoxO Signaling Pathway (921162); Glyoxylate And Dicarboxylate Metabolism Pathway (83002)

ncbi summary :

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]

uniprot summary :

Catalase: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. Homotetramer. Belongs to the catalase family. Protein type: Energy Metabolism - methane; Hydrolase; Apoptosis; Amino Acid Metabolism - tryptophan; EC 1.11.1.6; Oxidoreductase; Mitochondrial; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 11p13. Cellular Component: peroxisomal membrane; Golgi apparatus; peroxisomal matrix; focal adhesion; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; lysosome; plasma membrane; mitochondrial intermembrane space; peroxisome; cytosol. Molecular Function: antioxidant activity; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; enzyme binding; catalase activity; metal ion binding; heme binding; NADP binding; receptor binding; aminoacylase activity. Biological Process: cholesterol metabolic process; nucleobase, nucleoside and nucleotide metabolic process; hemoglobin metabolic process; purine base metabolic process; protein homotetramerization; activation of NF-kappaB transcription factor; positive regulation of phosphoinositide 3-kinase cascade; osteoblast differentiation; response to reactive oxygen species; response to vitamin E; response to hyperoxia; triacylglycerol metabolic process; UV protection; hydrogen peroxide catabolic process; ureteric bud development; inhibition of NF-kappaB transcription factor; positive regulation of cell division; response to hypoxia; aerobic respiration; purine nucleotide catabolic process; protein tetramerization; negative regulation of apoptosis; aging. Disease: Acatalasemia

size1 :

100 mg

price1 :

130 USD

size2 :

1 g

price2 :

290

more info or order :

MyBioSource product webpage