Apolipoprotein AII (ApoAII, ApoA2), Human Serum - Ultra Pure | MyBioSource MBS173021 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Apolipoprotein AII (ApoAII, ApoA2), Human Serum - Ultra Pure

catalog :

MBS173021

quantity :

0.1 mg

price :

230 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS173021

products type :

Protein

products full name :

Apolipoprotein AII (ApoAII, ApoA2), Human Serum - Ultra Pure

products short name :

Apolipoprotein AII

products name syn :

Apolipoprotein AII (APO AII), Human Serum - >=99% (SDS-PAGE)

other names :

apolipoprotein A-II preproprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; apolipoprotein A-II; Apolipoprotein A2Cleaved into the following 2 chains:Proapolipoprotein A-II; ProapoA-II; Truncated apolipoprotein A-IIAlternative name(s):Apolipoprotein A-II(1-76)

products gene name :

ApoA2

other gene names :

APOA2; APOA2; apoAII; Apo-AII; ApoA-II; Apo-AII; ApoA-II; ProapoA-II

uniprot entry name :

APOA2_HUMAN

sequence length :

100

purity :

>= 98% (SDS-PAGE)

form :

20mM Tris-HCl, 140mM sodium chloride, 0.5mM EDTA pH 8.0 with 0.02% sodium azide. Appearance: Frozen Liquid

concentration :

Protein Concentration: 1.0 - 5.0 mg/mL (Lowry)

storage stability :

At -20 degree C

other info1 :

Source: Human Plasma. UNSPSC Code: 51131909

other info2 :

Protein: 1.0mg/ml (Lowry). Recertification: 2 years

products categories :

Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; Apolipoprotein Aii (apo Aii)

products description :

MyBioSource sells human serum Apolipoprotein AII (ApoAII) for research, life science, and manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Ultra pure human Apolipoprotein AII is purified from delipidated HDL and is one of a family of evolutionarily related proteins which play a crucial role in lipid transport and metabolism. Serum levels of human ApoAII have been shown to be inversely correlated to the incidence of coronary heart disease and its expression to be limited to the liver and intestine.

ncbi gi num :

4502149

ncbi acc num :

NP_001634.1

ncbi gb acc num :

NM_001643.1

ncbi mol weight :

~17kDa

ncbi pathways :

Chylomicron-mediated Lipid Transport Pathway (106157); Complement And Coagulation Cascades Pathway (198880); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042)

ncbi summary :

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]

uniprot summary :

APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family. Protein type: Lipid-binding; Secreted; Secreted, signal peptide; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 1q23.3. Cellular Component: chylomicron; endoplasmic reticulum lumen; early endosome; extracellular region; cytosol. Molecular Function: lipid transporter activity; protein binding; protein homodimerization activity; lipase inhibitor activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; phospholipid binding; phosphatidylcholine binding; high-density lipoprotein binding; lipid binding; apolipoprotein receptor binding. Biological Process: positive regulation of catalytic activity; phototransduction, visible light; viral reproduction; protein folding; negative regulation of cholesterol transport; response to glucocorticoid stimulus; regulation of protein stability; diacylglycerol catabolic process; positive regulation of lipid catabolic process; cellular lipid metabolic process; negative regulation of lipase activity; negative regulation of lipid catabolic process; phospholipid efflux; regulation of cholesterol absorption; response to glucose stimulus; retinoid metabolic process; response to drug; cholesterol metabolic process; organ regeneration; protein amino acid oxidation; phospholipid catabolic process; positive regulation of interleukin-8 biosynthetic process; cholesterol efflux; lipoprotein metabolic process; negative regulation of cytokine secretion during immune response; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; response to estrogen stimulus; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; acute inflammatory response. Disease: Hypercholesterolemia, Familial

size1 :

0.1 mg

price1 :

230 USD

size2 :

1 mg

price2 :

710

more info or order :

MyBioSource product webpage