protein

Alpha-1 Microglobulin (A1M), Human Urine

MBS173009

0.1 mg

200 USD

Protein

Alpha-1 Microglobulin (A1M), Human Urine

Alpha-1 Microglobulin

Protein HC; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge; AMBP; Alpha-1 Macroglobulin (A1M), Human Urine - >=96% (SDS-PAGE)

protein AMBP preproprotein; Protein AMBP; protein AMBP; bikunin; uristatin; protein HC; trypstatin; uronic-acid-rich protein; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; complex-forming glycoprotein heterogeneous in charge; alpha-1-microglobulin/bikunin precursor; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge

AMBP

HCP; ITIL

AMBP; AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; HCP; ITIL; Protein HC; ITI-LC

AMBP_HUMAN

352

>= 96% (SDS-PAGE)

Lyophilized. Appearance: Off-white, lyophilized solid

2-8 degree C

Source: Human Urine

Reconstitution: 0.05 M phosphate buffer, pH >7.0, containing 0.15 M sodium chloride. Recertification: 2 years

Proteins; Antigens; Standards/controls; Native Proteins; Alpha-1 Microglobulin (a1m)

MyBioSource produces Alpha-1-Microglobulin (A1M) for clinical research and bulk diagnostics. Custom preparations, technical support, bulk quantities and aliquoting available. Human Alpha-1-Microglobulin (A1M) occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid and appears not only as a free monomer but also in complexes with IgA and human albumin. A1M is used in the diagnosis of tubular proteinuria (eg, Fanconi syndrome, tubulo-interstitial disorders). Increased excretion in the urine shows the presence of renal tubular disease and increased levels may be present in nephrotic syndrome. We can custom produce alpha-1-microglobulin to your specifications

4502067

NP_001624.1

NM_001633.3

P02760

~27,000

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 9q32-q33. Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; extracellular region; plasma membrane. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; IgA binding; heme binding; calcium oxalate binding; calcium channel inhibitor activity. Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage

0.1 mg

200 USD

1 mg

415

5 mg

1530