protein

Alpha-1 Antichymotrypsin (A1AT), Human Serum (Alpha 1-ACT)

MBS173007

0.1 mg

200 USD

Protein

Alpha-1 Antichymotrypsin (A1AT), Human Serum (Alpha 1-ACT)

Alpha-1 Antichymotrypsin

AACT; SERPINA3; Alpha 1-ACT; A1ACT ; Alpha-1 Antichymotrypsin (A1ACT), Human - >=95% (SDS-PAGE)

alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin; alpha-1-antichymotrypsin; serpin A3; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; Cell growth-inhibiting gene 24/25 protein; Serpin A3Alpha-1-antichymotrypsin His-Pro-less

ACT

SERPINA3; SERPINA3; ACT; AACT; GIG24; GIG25; AACT; ACT

AACT_HUMAN

423

>= 95% (SDS-PAGE)

Lyophilized

2-8 degree C

Source: Human Serum. UNSPSC Code: 51131904

Reconstitution: 0.05M phosphate buffer pH >7.0 containing 0.15M NaCl. Recertification: 2 years. Protein: Reported (A280 E=0.6)

Proteins; Antigens; Standards/controls; Native Proteins; Alpha-1 Antichymotrypsin (a1act)

MyBioSource is the leading supplier of Alpha-1 Antichymotrypsin (A1AT), Human Serum for research and diagnostic manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Human Alpha 1 antichymotrypsin is an alpha globulin glycoprotein and serpin. This Human Glycoprotein is found in alpha(1)-globulin region in human serum. Human Alpha 1-antichymotrypsin (ACT) (Alpha 1-ACT) inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro and also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. Human ACT is a member of the serpin superfamily. Human Alpha 1-Antichymotrypsin (Alpha 1-ACT) (ACT)can complex with human PSA to form human PSA-ACT complex which is used as an indicator of tumour mass and clinical stage of prostate cancer.

50659080

NP_001076.2

NM_001085.4

68 kDa

Selenium Pathway (198825)

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]

SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 14q32.1. Cellular Component: extracellular space; extracellular region; intracellular; nucleus. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; DNA binding. Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response

0.1 mg

200 USD

1 mg

600