catalog number :
MBS173001
products full name :
Bovine Serum Albumin (BSA) - Cohn Fraction V - Protease Free
products short name :
Albumin
products name syn :
BSA; ALB; Albumin (BSA, ALB) Cohn Fraction V, Protease Free - Bovine Serum
other names :
albumin; Serum albumin; serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42; albumin
other gene names :
ALB; ALB; FDAH; ANALBA; PRO0883; PRO0903; PRO1341
uniprot entry name :
ALBU_HUMAN
form :
Filtered through a 0.2um filter and lyophilized.
storage stability :
Aliquot and freeze at below -15 degree C after reconstitution. NOTE: AVOID MOISTURE
other info1 :
Appearance: Off-white to amber powder. Albumin Content: 100% (HPLC). Solubility: Completely Soluble
other info2 :
Protease: None Detected. Iron: 10ug/dL (Using 10% solution). Calcium: 0.3ug/dL (Using 10% solution). Chloride: 5 mEq/L(Using 10% solution). Sodium: 24 mEq/L(Using 10% solution). Absorbance at 440nm: <0.1. Absorbance at 550nm: <0.1. Loss on Drying: 4.5%. Bovine IgG: Below detectable limits. pH: 7.0 (Using 10% solution). Microbial Growth: No growth found . Recertification: March 6, 2018 . Handling: Handle as a potentially hazardous substance.
products categories :
Proteins; Antigens; Standards/controls; Native Proteins; Albumin (bsa; Alb) - Cohn Fraction V - Protease Free
products description :
MyBioSource produces and supplies bovine serum Albumin - Cohn Fraction V Protease Free for medical research and manufacturing to stabilize enzymes in matrices, use as a diluent and blocking agent in ELISA applications. Technical support, bulk quantities and aliquoting available. Solubility: Albumins are readily soluble in de-ionized water and can only precipitated by high concentrations of neutral salts. Bovine Serum Albumin help stabilize other solubilized proteins. Bovine Serum Albumin (BSA) is readily coagulated with heat. BSA as with other albumins are acidic proteins which occur in abundance in body fluids and tissues and is easily crystallized. What is BSA?: Bovine serum albumin can be used as a diluent or a blocking agent in numerous applications including ELISA, blots and immuno-histochemistry. In restriction digests, bovine serum albumin is used to stabilize some enzymes during digestion of DNA and to prevent adhesion of the enzyme to reaction tubes and other vessels. BSA doesn't affect other enzymes that do not need it for stabilization and is used because of its stability.
ncbi acc num :
CAA00606.1
ncbi mol weight :
66317.8
ncbi pathways :
Bile Acid And Bile Salt Metabolism Pathway (106144); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation, Signaling And Aggregation Pathway (106034)
ncbi summary :
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
uniprot summary :
albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide; Carrier. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus. Molecular Function: antioxidant activity; toxin binding; protein binding; enzyme binding; copper ion binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding. Biological Process: platelet activation; receptor-mediated endocytosis; sodium-independent organic anion transport; bile acid metabolic process; maintenance of mitochondrion localization; lipoprotein metabolic process; hemolysis by symbiont of host red blood cells; cellular response to starvation; bile acid and bile salt transport; response to mercury ion; response to organic substance; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis. Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic