Lactoferrin, Goat Polyclonal anti-Human Antibody | MyBioSource MBS171031 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Lactoferrin, Goat Polyclonal anti-Human Antibody

catalog :

MBS171031

quantity :

1 mg

price :

250 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS171031

products type :

Antibody

products full name :

Lactoferrin, Goat Polyclonal anti-Human Antibody

products short name :

Lactoferrin

products name syn :

Lactoferrin, Polyclonal anti-Human Antibody

other names :

lactoferrin, partial; Lactotransferrin; lactotransferrin; kaliocin-1; lactoferricin; lactoferroxin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; epididymis luminal protein 110; lactotransferrin; Growth-inhibiting protein 12; TalalactoferrinCleaved into the following 5 chains:Lactoferricin-H; Lfcin-H; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C

other gene names :

LTF; LTF; LF; HLF2; GIG12; HEL110; GIG12; LF; Lactoferrin; Lfcin-H

uniprot entry name :

TRFL_HUMAN

clonality :

Polyclonal

host :

Goat

sequence length :

purity :

Affinity Purified

form :

Liquid

concentration :

AB Concentration: Typically 1.0 mg/mL

storage stability :

2-8 degree C

other info2 :

pH: 7.2. Immunogen: Goat

products categories :

Antibodies; Polyclonal; Lactoferrin (lf); Polyclonal Antibody

products description :

Polyclonal Antibody anti-human lactoferrin PROCEDURE: Goats were immunized with Human purified human neutrophil lactoferrin in Freunds adjuvant. The goats were bled, serum collected and the anti-neutrophil lactoferrin was immunity purified off an antigen containing imunnoabsorbant. Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available. Polyclonal Antibody anti-human Lactoferrin SPECIFICATIONS: By IEP and ELISA, the antibodies with human lactoferrin. Inquire polyclonal Antibody anti-human lactoferrin bulk quantities of 100-500 mg. Polyclonal Lactoferrin antibody can be concentrated to your requirements.

ncbi gi num :

263312

ncbi acc num :

AAB24877.1

ncbi mol weight :

73,161 Da

ncbi pathways :

Amyloids Pathway (366238); Disease Pathway (530764); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Mtb Iron Assimilation By Chelation Pathway (1127564); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); Response Of Mtb To Phagocytosis Pathway (1127560)

ncbi summary :

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

uniprot summary :

LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.21.-. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule. Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; serine-type endopeptidase activity; iron ion binding. Biological Process: interaction with host; negative regulation of lipopolysaccharide-mediated signaling pathway; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; activation of NF-kappaB transcription factor; regulation of cytokine production; retinal homeostasis; positive regulation of osteoblast differentiation; negative regulation of viral genome replication; innate immune response in mucosa; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of ATPase activity; iron assimilation by chelation and transport; negative regulation of viral reproduction; negative regulation of apoptosis

size1 :

1 mg

price1 :

250 USD

size2 :

3 mg

price2 :

570

more info or order :

MyBioSource product webpage