catalog number :
MBS171029
products full name :
Haptoglobin, Goat Polyclonal Antibody Anti-Human
products short name :
Haptoglobin
products name syn :
Haptoglobin (Hp), Goat Polyclonal anti-Human Antibody
other names :
haptoglobin, partial; Haptoglobin-related protein; haptoglobin-related protein; Haptoglobin-related locus; haptoglobin-related protein
other gene names :
HPR; HPR; HP; A-259H10.2
uniprot entry name :
HPTR_HUMAN
purity :
Affinity Purified
concentration :
AB Concentration: Typically 1.0 mg/mL
storage stability :
2-8 degree C
other info2 :
Recertification: 2 years. Immunogen: Human Haptoglobin
products categories :
Antibodies; Polyclonal; Haptoglobin (hp); Polyclonal Antibody
products description :
Polyclonal anti-human Haptoglobin procedure: Purification of Goat anti-human haptoglobin: Goats were immunized with highly purified human haptoglobin. After several injections serum was collected and solid phase absorbed to ensure anti-human haptoglobin specificity. The antiserum was then affinity purified off an antigen containing immunoabsorbant. The anti-human haptoglobin is useful for ELISA and blotting applications. The affinity purified anti human haptoglobin forms a single preciptin band with human serum haptoglobin and purified human haptoglobin by immunoelectrophoresis and double diffusion. Western Blots 1:1,000-1:5000 ELISA coating 1:200-1:500. Polyclonal goat anti-Human Haptoglobin BULK QUANTITIES 1,000 mg single lot sizes available.
ncbi acc num :
AAA52686.1
ncbi mol weight :
43,078 Da
ncbi pathways :
African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)
ncbi summary :
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
uniprot summary :
HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 16q22.1. Cellular Component: extracellular region. Molecular Function: hemoglobin binding; catalytic activity. Biological Process: receptor-mediated endocytosis; metabolic process