catalog number :
MBS171026
products full name :
Alpha Fetoprotein, Polyclonal Whole Antiserum Anti-Human (AFP)
products short name :
Alpha-Fetoprotein
products name syn :
Alpha-Fetoprotein (AFP), Goat Polyclonal Whole Antiserum
other names :
alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
concentration :
AB Concentration: Typically 1.0 mg/mL
storage stability :
2-8 degree C
other info2 :
Recertification: 2 years. Immunogen: Human Alpha-Fetoprotein
products categories :
Antibodies; Antisera; Alpha-fetoprotein (afp); Polyclonal Whole Antiserum
products description :
Polyclonal anti-human Alpha Fetoprotein specificity: This antibody is monospecific to alpha-fetoprotein by immunoelectrophoresis and gel diffusion techniques. Technical support, bulk quantities and aliquoting available. Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available.
ncbi acc num :
EAX05681.1
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of