antibody

C-Reactive Protein (CRP), Polyclonal Antibody Anti-Human Affinity Purified

MBS171025

1 mg

230 USD

polyclonal

goat

nonconjugated

Antibody

C-Reactive Protein (CRP), Polyclonal Antibody Anti-Human Affinity Purified

C-Reactive Protein

C-Reactive Protein (CRP), Goat Polyclonal Antibody

C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related

CRP; CRP; PTX1; PTX1

CRP_HUMAN

Polyclonal

Goat

224

Affinity Purified

Liquid

AB Concentration: >= 1.0 mg/mL

2-8 degree C

Recertification: 3 years. Immunogen: Human C-Reactive Protein

Antibodies; Polyclonal; C-reactive Protein (crp); Polyclonal Antibody

MyBioSource is a supplier of affinity purified C-Reactive Protein Polyclonal anti-Human antibody for diagnostic manufacturing and research uses. Technical support, bulk quantities and aliquoting available. BULK QUANTITIES of 1,000 mg single lot sizes of Polyclonal Antibody goat anti-human C-Reactive Protein (CRP). Procedure: Goats were immunized with Human CRP C-Reactive Protein. After multiple immunizations in Freund's adjuvant, the goats were bled and serum collected. Reacts only with C-Reactive Protein CRP by ELISA, IEP and Double Diffusion. Western Blots 1:1,000-1:5,000 ELISA 1:5,000-20,000

30224

CAA39671.1

P02741

10,415 Da

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; virion binding; cholesterol binding; low-density lipoprotein binding; calcium ion binding. Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging

1 mg

230 USD

3 mg

405