catalog number :
MBS171019
products full name :
Retinol Binding Protein (RBP), Polyclonal Anti-Human Affinity Purified
products short name :
Retinol Binding Protein
products name syn :
Retinol Binding Protein (RBP), Polyclonal Antibody
other names :
retinol-binding protein 4; Retinol-binding protein 4; retinol-binding protein 4; RBP; PRBP; plasma retinol-binding protein; retinol binding protein 4, plasma; Plasma retinol-binding protein; PRBP; RBP
other gene names :
Rbp4; Rbp4; RBPA; PRBP; RBP
uniprot entry name :
RET4_RAT
purity :
Affinity Purified
concentration :
AB Concentration: Typically >1.0 mg/mL
storage stability :
2-8 degree C
other info2 :
pH: 7.2. Immunogen: Human Retinol Binding Protein
products categories :
Antibodies; Polyclonal; Retinol Binding Protein (rbp); Polyclonal Antibody
products description :
Polyclonal anti-Human Retinol Binding(anti-RBP) Procedure: Chickens were immunized with highly purified human Retinol Binding Protein (RBP). The resulting anti-human retinol binding protein (RBP) was solid phase absorbed then affinity purified off an antigen containing immunoabsorbant. Inquire on Bulk quantities of 50-100 mg of Polyclonal anti-human Retinol Protein. Polyclonal anti-Human Retinol Binding Specification: This anti-Human Retinol Binding Protein is suitable for depletion, ELISA and blotting applications. Western Blots 1:1,000 ELISA coating 1:200-1:500. Inquire on our custom polyclonal antibody production. We can host from any species and cross link to your requirements. Custom Polyclonal antibody concentrations available. What is Retinol Binding Protein: Human Retinol binding protein (RBP) is responsible for binding and transporting retinol (vitamin A). human retinol binding protein (RBP) has a binding site for one molecule of retinol and circulates in the plasma together with prealbumin in the form of a protein complex in a molar ratio of 1:1. This binding to prealbumin prevents greater glomerular losses of the human retinol-binding protein. Only the retinol-free form of the retinol-binding protein, which has no affinity for prealbumin, undergoes glomerular filtration unhindered as a result of its low molecular weight; human retinol binding protein (RBP) is re-absorbed by the tubular cells and catabolized there. This explains the elevated serum level of human retinol-binding protein in advanced chronic renal insufficiency. Since human retinol-binding protein and human prealbumin are synthesized in the liver, their serum concentrations are reduced in acute and chronic hepatic diseases. Decreased concentrations of Human Retinol binding Protein (RBP)have also been observed in cystic fibrosis.
ncbi acc num :
NP_037294.1
ncbi gb acc num :
NM_013162.1
ncbi mol weight :
23,220 Da
ncbi pathways :
Disease Pathway 1121849!!Diseases Associated With Visual Transduction Pathway 1121888!!Retinoid Cycle Disease Events Pathway 1121889!!Retinoid Metabolism And Transport Pathway 1120793!!Retinol Metabolism Pathway 219784!!Signal Transduction Pathway 1120558!!The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway 1120794!!Visual Phototransduction Pathway 1120792
ncbi summary :
may play a role in vitamin A transport [RGD, Feb 2006]