protein

Creatine Kinase MB Isoenzyme, Human Heart

MBS170403

100 Units

240 USD

Protein

Creatine Kinase MB Isoenzyme, Human Heart

[Creatine Kinase MB]

[CKMB, CK-MB]

[CKMB]

Human Heart

Purified (Control Grade)

0.2 micron filtered solution in 10 mM tris-succinate, 2 mM DTT , 2 mM EDTA, 175 mM sodium chloride, pH 7.0 with glycerol added to 50% (v/v)

Store at -20°C

CAS Number: 9001-15-4. E.C Number: 2.7.3.2. Appearance: Clear, ligth brown solution. Activity: 1,510 U/mL Dimension R Clinical Chemistry System). Unit definition: One unit wil catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C. Protein: 14.6 mg/mL(Coomasie). Specific activity: 104 U/mg protein. Electrophoresis: >= 99% CKMB (Helena Quick Gel R CK). Contaminants: GOT <1%. LDH <1%. Country of origin: United States of America . (Note: Donor material originates from TSE, CJD and vCJD- free countries, and mandatorily reports requirements for occurrence of these diseases). Handling: Handle as a potentially hazardous substance. Recovery: Centrifuge briefly to ensure complete recovery.

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Creatine Kinase Mb (ck-mb)

MyBioSource produces human cardiac Creatine Kinase MB (CK-MB) isoenzyme for research, life science and use as a control or calibrator for diagnostic manufacturing. Custom preparations, technical support, bulk quantities and aliquoting available. Human Creatine Kinase is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). It can also used for monitoring reperfusion during thrombolytic therapy following AMI. Testing is performed when the total Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Creatine Kinase MM, BB, and MB isoenzymes exist.

21536288

NP_001815.2

NM_001824.4

84,000

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

100 Units

240 USD

1000 Units

1035