protein

Hemopexin, Human Plasma

MBS170373

1 mg

390 USD

Protein

Hemopexin, Human Plasma

Hemopexin

Haemopexin; HPX; beta-1B-glycoprotein; Hemopexin (HPX)

hemopexin; Hemopexin; hemopexin; beta-1B-glycoprotein; hemopexin; Beta-1B-glycoprotein

HPX

HPX; HPX; HX

HEMO_HUMAN

462

>= 95% (SDS-PAGE)

Lyophilized from phosphate, sodium chloride and potassium chloride, pH 7.4. Appearance: White powder

Store at -20 degree C. Protect from moisture. Shipping: cold packs

Source: Human Plasma. EC Number: 3.2.1.35. Protein: 1.0 mg/vial(E 0.1% 280 = 1.97)

Reconstitution: Reconstitution with purified water to a concentration of 2-4 mg protein/mL. Centrifuge briefly to ensure complete recovery. Prepare further dilutions with phosphate buffered saline, pH7.4

Proteins; Antigens; Standards/controls; Native Proteins; Hemopexin (hpx)

MyBioSource produces and manufactures high purity human plasma Hemopexin research and diagnostic manufacturing uses. Custom preparations, technical support, bulk quantities and aliquoting available. Hemopexin levels in serum reflect how much heme is present in the blood. Therefore, low hemopexin levels indicates that there has been significant degradation of heme containing compounds and hemopexin is made to scavenge any heme it can. Low hemopexin levels are one of the diagnostic features of a hemolytic anemia.

11321561

NP_000604.1

NM_000613.2

P02790

~57,000

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Scavenging Of Heme From Plasma Pathway (771600)

This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]

HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11p15.5-p15.4. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; metal ion binding; heme transporter activity. Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; receptor-mediated endocytosis; positive regulation of tyrosine phosphorylation of Stat1 protein; heme transport; positive regulation of immunoglobulin production; viral reproduction; cellular iron ion homeostasis; hemoglobin metabolic process; heme metabolic process

1 mg

390 USD