This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Prostaglandin D2, PGD2 ELISA Kit
catalog :
MBS162622
quantity :
48-Strip-Wells
price :
260 USD
product information
catalog number :
MBS162622
products type :
ELISA Kit
products full name :
Human Prostaglandin D2, PGD2 ELISA Kit
products short name :
[Prostaglandin D2, PGD2]
other names :
[prostaglandin D2 receptor 2; Prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD_antigen: CD294]
products gene name :
[PGD2]
other gene names :
[PTGDR2; PTGDR2; DP2; DL1R; CD294; CRTH2; GPR44; CRTH2; DL1R; GPR44]
reactivity :
Human
sequence length :
395
storage stability :
Store at 2 to 8 degree C for 6 months.
ncbi gi num :
153791424
ncbi acc num :
NP_004769.2
ncbi gb acc num :
NM_004778.2
uniprot acc num :
Q9Y5Y4
ncbi mol weight :
43,268 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); Eicosanoid Ligand-binding Receptors Pathway (106370); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Prostanoid Ligand Receptors Pathway (106371)
ncbi summary :
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
uniprot summary :
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
size1 :
48-Strip-Wells
price1 :
260 USD
size2 :
96-Strip-Wells
price2 :
395
size3 :
5x96-Strip-Wells
price3 :
1610
size4 :
10x96-Strip-Wells
price4 :
3135
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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