catalog number :
MBS161261
products type :
ELISA Kit
products full name :
Human Annexin A2, Anxa2 ELISA Kit
products short name :
[Annexin A2, Anxa2]
other names :
[annexin A2 isoform 2; Annexin A2; annexin A2; annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36]
products gene name :
[Anxa2]
other gene names :
[ANXA2; ANXA2; P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270; ANX2; ANX2L4; CAL1H; LPC2D; PAP-IV]
storage stability :
Store at 2 to 8 degree C for 6 months.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.1ng/ml - 40ng/ml. Sensitivity: 0.04ng/ml
other info2 :
Intra-Assay: CV<8% . Inter-Assay: CV<10%
products description :
Intended Uses: This sandwich kit is for the accurate quantitative detection of human Annexin A2 (also known as Anxa2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human Anxa2 antibody. Anxa2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human Anxa2 Antibody is added and binds to Anxa2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated Anxa2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human Anxa2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm
ncbi acc num :
NP_001129487.1
ncbi gb acc num :
NM_001136015.2
ncbi mol weight :
40,411 Da
ncbi pathways :
Prostaglandin Synthesis And Regulation Pathway (198912)
ncbi summary :
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
size4 :
10x96-Strip-Wells