catalog number :
MBS160737
products type :
ELISA Kit
products full name :
Mouse C-type natriuretic peptide, CNP ELISA Kit
products short name :
[C-type natriuretic peptide, CNP]
other names :
[C-type natriuretic peptide preproprotein; C-type natriuretic peptide; C-type natriuretic peptide; natriuretic peptide C]
products gene name :
[CNP]
other gene names :
[NPPC; NPPC; CNP; CNP2; CNP2]
storage stability :
Store at 2 to 8 degree C for 6 months.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3ng/L - 900ng/L. Sensitivity: 1.52ng/L
other info2 :
Intra-Assay: CV<8% . Inter-Assay: CV<10%
products description :
Intended Uses: This sandwich kit is for the accurate quantitative detection of Mouse C-type Natriuretic Peptide (also known as CNP) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Mouse CNP antibody. CNP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse CNP Antibody is added and binds to CNP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CNP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse CNP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
ncbi acc num :
NP_077720.1
ncbi gb acc num :
NM_024409.3
ncbi mol weight :
13,246 Da
ncbi summary :
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015]
uniprot summary :
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 ().
size4 :
10x96-Strip-Wells