catalog number :
MBS160274
products type :
ELISA Kit
products full name :
Guinea Pig Antithrombin (AT) ELISA Kit
products short name :
[Antithrombin (AT)]
other names :
[antithrombin; Antithrombin-III; antithrombin-III; serpin family C member 1; Serpin C1]
products gene name :
[AT]
other gene names :
[SERPINC1; SERPINC1; AT3; AT3D; ATIII; THPH7; ATIII-R2; AT3; ATIII]
storage stability :
Store at 2 to 8 degree C for 6 months.
ncbi acc num :
CAA48690.1
ncbi mol weight :
52,602 Da
ncbi pathways :
Common Pathway (106060); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Glypican 1 Network Pathway (138010); Hemostasis Pathway (106028)
ncbi summary :
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]
uniprot summary :
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
size4 :
10x96-Strip-Wells