catalog number :
MBS160116
products type :
ELISA Kit
products full name :
Human beta defensin 2, HBD2 ELISA Kit
products short name :
[beta defensin 2, HBD2]
other names :
[beta defensin 2; Beta-defensin 4A; beta-defensin 4A; defensin beta 4A; Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1]
products gene name :
[HBD2]
other gene names :
[DEFB4A; DEFB4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102; DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1]
storage stability :
Store at 2 to 8 degree C for 6 months.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Assay Type: Quantitative Sandwich. Detection Range: 10ng/L - 4000ng/L. Sensitivity: 5.31ng/L
other info2 :
Intra-Assay: CV<8% . Inter-Assay: CV<10%
products description :
Intended Uses: This sandwich kit is for the accurate quantitative detection of human Beta Defensin 2 (also known as HBD2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates. Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human HBD2 antibody. HBD2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human HBD2 Antibody is added and binds to HBD2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated HBD2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human HBD2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
ncbi acc num :
AAC69554.1
ncbi mol weight :
7,038 Da
ncbi pathways :
Beta Defensins Pathway (530759); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]
uniprot summary :
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036).
size4 :
10x96-Strip-Wells