product summary
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company name :
MyBioSource
product type :
antibody
product name :
LANCL2 Antibody
catalog :
MBS154355
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS154355 image 1
Western blot analysis of LANCL2 in human brain tissue lysate with LANCL2 antibody at 1 g/ml.
image 2 :
MyBioSource MBS154355 image 2
Immunohistochemistry of LANCL2 in mouse brain tissue with LANCL2 antibody at 5 g/mL.
product information
catalog number :
MBS154355
products type :
Antibody
products full name :
LANCL2 Antibody
products short name :
[LANCL2]
products name syn :
[LanC lantibiotic synthetase component C-like 2, GPR69B, LanC-like protein 2, TASP, Testis-specific adriamycin sensitivity protein]
other names :
[lanC-like protein 2; LanC-like protein 2; lanC-like protein 2; LanC like 2; Testis-specific adriamycin sensitivity protein]
products gene name :
[LANCL2]
other gene names :
[LANCL2; LANCL2; TASP; GPR69B; GPR69B; TASP]
uniprot entry name :
LANC2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
450
specificity :
LANCL2 antibody is human, mouse and rat reactive.
purity :
Affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
LANCL2 antibody can be used for the detection of LANCL2 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: LANCL2 antibody was raised against a 16 amino acid peptide from near the amino terminus of human LANCL2. The immunogen is located within amino acids 30-80 of LANCL2. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: Human Brain Tissue Lysate
other info2 :
Conjugate: Unconjugated
products categories :
Signal Transduction
products description :
LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1). It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3). LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4).
products references :
Mayer H, Pongratz M, and Prohaska R. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family. DNA Seq. 2001; 12:161-6. Sturla L, Fresia C, Guida L, et al. Binding of abscisic acid to human LANCL2. Biochem. Biophys. Res. Commun. 2011; 415:390-5. Landlinger C, Salzer U, and Prohaska R. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin. Biochim. Biophys. Acta. 2006; 1758:1759-67. Zeng M, van der Donk WA, Chen J. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol. Biol. Cell 2014; 25:3954-61.
ncbi gi num :
8923911
ncbi acc num :
NP_061167
ncbi gb acc num :
NM_018697.3
uniprot acc num :
Q9NS86
ncbi mol weight :
Predicted: 50 kDa. Observed: 48 kDa
uniprot summary :
LANCL2: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. Belongs to the LanC-like protein family. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 7q31.1-q31.33. Cellular Component: cortical actin cytoskeleton; cytoplasm; cytosol; nucleus; plasma membrane. Molecular Function: ATP binding; catalytic activity; GTP binding; phosphatidylinositol 3-phosphate binding; phosphatidylinositol-5-phosphate binding; protein binding. Biological Process: metabolic process; negative regulation of transcription, DNA-dependent; positive regulation of abscisic acid mediated signaling
size1 :
0.1 mg
price1 :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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