protein

TREM1 Peptide

MBS153887

0.05 mg

140 USD

Blocking Peptide

TREM1 Peptide

[TREM1]

[CD354; TREM-1; Triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1]

[triggering receptor expressed on myeloid cells 1 isoform 1; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1; CD_antigen: CD354]

[TREM1]

[TREM1; TREM1; CD354; TREM-1; TREM-1]

TREM1_HUMAN

234

Liquid

200 ug/mL

Store TREM1 peptide at -20 degree C, stable for one year.

Blocking (BL)

TREM1 peptide is used for blocking the activity of TREM1 antibody.

Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 17 amino acids near the amino terminus of human TREM1.

8924262

NP_061113

NM_018643.3

Q9NP99

25,574 Da

Cell Surface Interactions At The Vascular Wall Pathway (106062); DAP12 Interactions Pathway (685549); Hemostasis Pathway (106028); Immune System Pathway (106386); Innate Immune System Pathway (106387)

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 6p21.1. Cellular Component: integral to membrane; extracellular region; plasma membrane. Molecular Function: receptor activity. Biological Process: neutrophil chemotaxis; innate immune response; cytokine secretion during immune response; blood coagulation; leukocyte migration; chemokine metabolic process; humoral immune response

0.05 mg

140 USD