catalog number :
MBS153778
products type :
Blocking Peptide
products full name :
IL-9 Peptide
products short name :
[IL-9]
products name syn :
[P40; HP40; IL-9; Interleukin-9; Cytokine P40; interleukin 9]
other names :
[interleukin-9; Interleukin-9; interleukin-9; cytokine P40; p40 cytokine; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40; interleukin 9; Cytokine P40; T-cell growth factor P40]
products gene name :
[IL9]
other gene names :
[IL9; IL9; P40; HP40; IL-9; IL-9]
uniprot entry name :
IL9_HUMAN
concentration :
200 ug/mL
storage stability :
Store IL-9 peptide at -20°C, stable for one year.
tested application :
Blocking (BL)
app notes :
The peptide is used for blocking the activity of IL-9 antibody. It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37 degree C.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 16 amino acids near the carboxy terminus of human IL-9.
ncbi gb acc num :
NM_000590.1
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL-9 Signaling Pathway (198883); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); TCR Signaling Pathway (198862)
ncbi summary :
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
uniprot summary :
IL9: Supports IL-2 independent and IL-4 independent growth of helper T-cells. Belongs to the IL-7/IL-9 family. Protein type: Secreted; Secreted, signal peptide; Cytokine. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: extracellular space. Molecular Function: growth factor activity; interleukin-9 receptor binding; cytokine activity. Biological Process: positive regulation of cell proliferation; immune response; inflammatory response; positive regulation of cell growth; positive regulation of interleukin-5 biosynthetic process