product summary
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company name :
MyBioSource
product type :
antibody
product name :
NINJ1 Antibody
catalog :
MBS153659
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
image
image 1 :
Western blot analysis of NINJ1 in human brain tissue lysate with NINJ1 antibody at 1 g/ml.
image 2 :
Immunohistochemistry of NINJ1 in mouse brain tissue with NINJ1 antibody at 5 g/ml.
image 3 :
Immunofluorescence of NINJ1 in mouse brain tissue with NINJ1 antibody at 20 g/ml.
product information
catalog number :
MBS153659
products type :
Antibody
products full name :
NINJ1 Antibody
products short name :
[NINJ1]
products name syn :
[NINJ1; NIN1; NINJURIN; Ninjurin-1; Nerve injury-induced protein 1; ninjurin 1]
other names :
[ninjurin-1; Ninjurin-1; ninjurin-1; nerve injury-induced protein 1; nerve injury-induced protein-1; ninjurin 1; Nerve injury-induced protein 1]
products gene name :
[NINJ1]
other gene names :
[NINJ1; NINJ1; NIN1; NINJURIN]
uniprot entry name :
NINJ1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
specificity :
NINJ1 antibody is human, mouse and rat reactive.
purity :
NINJ1 antibody is affinity chromatography purified via peptide column.
form :
Liquid supplied in PBS containing 0.02% sodium azide.
concentration :
1 mg/mL
storage stability :
NINJ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
app notes :
NINJ1 antibody can be used for detection of NINJ1 by Western blot at 1-2 g/ml. Antibody can also be used for immunohistochemistry starting at 5 g/mL. For immunofluorescence start at 20 g/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Conjugate: Unconjugated. Immunogen: NINJ1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human NINJ1. The immunogen is located within the last 50 amino acids of NINJ1.
other info2 :
Positive Control: MBS151732 (Human Brain Tissue Lysate)
products description :
Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3).
ncbi gi num :
148922911
ncbi acc num :
NP_004139
ncbi gb acc num :
NM_004148.3
uniprot acc num :
Q92982
ncbi mol weight :
Predicted: 17 kDa. Observed: 16 kDa
ncbi summary :
The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]
uniprot summary :
NINJ1: Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations. Belongs to the ninjurin family. Protein type: Membrane protein, integral; Cell development/differentiation; Cell adhesion; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 9q22. Cellular Component: integral to membrane. Biological Process: nervous system development; tissue regeneration; cell adhesion; positive regulation of cell-matrix adhesion
size1 :
0.1 mg
price1 :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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