product summary
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company name :
MyBioSource
product type :
antibody
product name :
DCNP1 Antibody
catalog :
MBS153585
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
image
image 1 :
Western blot analysis of DCNP1 in mouse skeletal muscle tissue lysate with DCNP1 antibody at (A) 1 and (B) 2 g/ml.
image 2 :
Immunohistochemistry of DCNP1 in mouse skeletal muscle tissue with DCNP1 antibody at 5 g/ml.
image 3 :
Immunofluorescence of DCNP1 in mouse skeletal muscle tissue with DCNP1 antibody at 20 g/ml.
product information
catalog number :
MBS153585
products type :
Antibody
products full name :
DCNP1 Antibody
products short name :
[DCNP1]
products name syn :
[DCNP1; DCNP1; C5orf20; Dendritic cell nuclear protein 1]
other names :
[dendritic cell nuclear protein 1; Dendritic cell nuclear protein 1; dendritic cell nuclear protein 1; dendritic cell nuclear protein-1; dendritic cell-associated nuclear protein; Dendritic cell nuclear protein-1; Dendritic cell-associated nuclear protein]
products gene name :
[C5orf20]
other gene names :
[DCANP1; DCANP1; DCNP1; C5orf20]
uniprot entry name :
DCNP1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
244
specificity :
DCNP1 antibody is human, mouse and rat reactive.
purity :
DCNP1 antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
DCNP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Praffin (IHC-P), Immunofluorescence (IF)
app notes :
DCNP1 antibody can be used for detection of DCNP1 by Western blot at 1 - 2 ug/ml. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL. Optimal dilutions for each application to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Conjugate: Unconjugated. Immunogen: DCNP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human DCNP1. The immunogen is located within the first 50 amino acids of DCNP1. Buffer: DCNP1 Antibody is supplied in PBS containing 0.02% sodium azide. Positive Control: Catalog No. MBS151630 - Mouse Skeletal Muscle Tissue Lysate
products description :
The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1). It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2,3). DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4).
ncbi gi num :
18677770
ncbi acc num :
NP_570900
ncbi gb acc num :
NM_130848.2
uniprot acc num :
Q8TF63
ncbi mol weight :
Predicted: 27 kDa. Observed: 24 kDa
ncbi summary :
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]
uniprot summary :
DCANP1: Binds with and transactivates the corticotropin- releasing hormone (CRH) promoter. {ECO:0000269 PubMed:20693543}. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: cytoplasm; nucleus. Molecular Function: DNA binding. Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
size1 :
0.1 mg
price1 :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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