catalog number :
MBS153497
products full name :
IL-9 Antibody
products short name :
[IL-9]
products name syn :
[IL-9 Antibody : P40; HP40; IL-9; Interleukin-9; Cytokine P40]
other names :
[interleukin-9; Interleukin-9; interleukin-9; cytokine P40; p40 cytokine; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40; interleukin 9; Cytokine P40; T-cell growth factor P40]
products gene name :
[IL9]
other gene names :
[IL9; IL9; P40; HP40; IL-9; IL-9]
uniprot entry name :
IL9_HUMAN
specificity :
IL-9 antibody is human specific. IL-9 antibody is predicted to no cross-react with IL-7.
purity :
IL-9 Antibody is affinity chromatography purified via peptide column.
form :
Liquid; IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.
storage stability :
IL-9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
app notes :
IL-9 antibody can be used for detection of IL-9 by Western blot at 1 - 2 ug/ml. Antibody validated:. Western Blot in human samples. Immunohistochemistry in human samples. Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: IL-9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-9. The immunogen is located within the last 50 amino acids of IL-9. Conjugate: Unconjugated
products description :
Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2). It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3). The IL-9 gene has been identified as a candidate gene for asthma (4). Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5).
ncbi gb acc num :
NM_000590.1
ncbi mol weight :
Predicted: 13 kDa. Observed: 22kDa
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL-9 Signaling Pathway (198883); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); TCR Signaling Pathway (198862)
ncbi summary :
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
uniprot summary :
IL9: Supports IL-2 independent and IL-4 independent growth of helper T-cells. Belongs to the IL-7/IL-9 family. Protein type: Cytokine; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: extracellular space. Molecular Function: growth factor activity; interleukin-9 receptor binding; cytokine activity. Biological Process: positive regulation of cell proliferation; immune response; inflammatory response; positive regulation of cell growth; positive regulation of interleukin-5 biosynthetic process