product summary
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company name :
MyBioSource
product type :
antibody
product name :
BATF3 Antibody
catalog :
MBS153454
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS153454
products type :
Antibody
products full name :
BATF3 Antibody
products short name :
BATF3
products name syn :
Basic leucine zipper transcriptional factor ATF-like 3; SNFT; JDP1; JUNDM1; basic leucine zipper transcription factor, ATF-like 3
other names :
basic leucine zipper transcriptional factor ATF-like 3; Basic leucine zipper transcriptional factor ATF-like 3; basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; Jun dimerization protein 1; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells; 21 kDa small nuclear factor isolated from T-cells; basic leucine zipper transcription factor, ATF-like 3; 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
products gene name :
BATF3
other gene names :
BATF3; BATF3; JDP1; SNFT; JUNDM1; SNFT; B-ATF-3
uniprot entry name :
BATF3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
127
specificity :
BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.
purity :
BATF3 antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
BATF3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
BATF3 body can be used for detection of BATF3 by Western blot at 1 - 2 ug/ml. Optimal dilutions for each application to be determined by the researcher.
other info1 :
Conjugate: Unconjugated. Immunogen: BATF3 antibody was raised against a 16 amino acid peptide near the amino terminus of human BATF3. Buffer: BATF3 antibody is supplied in PBS containing 0.02% sodium azide.
products description :
BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1,2). BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3,4).
ncbi gi num :
8924246
ncbi acc num :
NP_061134
ncbi gb acc num :
NM_018664.2
ncbi mol weight :
Predicted: 14 kDa. Observed: 17 kDa
ncbi pathways :
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Calcium Signaling In The CD4+ TCR Pathway (137941)
ncbi summary :
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
uniprot summary :
BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5 -TGA[CG]TCA-3 ). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 1q32.3. Cellular Component: nucleus. Molecular Function: transcription corepressor activity; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; response to virus; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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