TRPV1 Antibody | MyBioSource MBS153345 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

TRPV1 Antibody

catalog :

MBS153345

quantity :

0.1 mg

price :

375 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of TRPV1 in K562 cell lysate with TRPV1 antibody at 1 g/mL.

product information

catalog number :

MBS153345

products type :

Antibody

products full name :

TRPV1 Antibody

products short name :

[TRPV1]

products name syn :

[TRPV1; VR1; VR1; Transient receptor potential cation channel subfamily V member 1; Capsaicin receptor; TrpV1; transient receptor potential cation channel, subfamily V, member 1]

other names :

[transient receptor potential cation channel subfamily V member 1; Transient receptor potential cation channel subfamily V member 1; transient receptor potential cation channel subfamily V member 1; OTRPC1; capsaicin receptor; osm-9-like TRP channel 1; vanilloid receptor subtype 1; transient receptor potential vanilloid 1a; transient receptor potential vanilloid 1b; transient receptor potential cation channel, subfamily V, member 1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1]

products gene name :

[TRPV1]

other gene names :

[TRPV1; TRPV1; VR1; VR1; TrpV1; OTRPC1]

uniprot entry name :

TRPV1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

839

purity :

TRPV1 Antibody is affinity chromatography purified via peptide column.

form :

TRPV1 Antibody is supplied in PBS containing 0.02% sodium azide.

concentration :

1 mg/mL

storage stability :

TRPV1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

tested application :

ELISA (EL/EIA), Western Blot (WB)

app notes :

TRPV1 antibody can be used for detection of TRPV1 by Western blot at 1 - 2 ug/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application to be determined by the researcher.

image1 heading :

Western Blot (WB)

other info1 :

Homology: Predicted species reactivity based on immunogen sequence: Guinea pig: (81%), Mouse: (75%). Immunogen: Rabbit polyclonal TRPV1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TRPV1. The immunogen is located within the last 50 amino acids of TRPV1. Positive Control: 1) Cat# MBS151739 - K562 Cell Lysate. Conjugate: Unconjugated. Physical State: Liquid

products description :

TRPV1 Antibody: TRPV1 is a receptor for capsaicin, the main pungent ingredient in hot chili peppers, and elicits a sensation of burning pain by selectively activating sensory neurons. TRPV1 is a non-selective cation channel that is structurally related to members of the TRP family of ion channels such as TRPC3 and TRPC6. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

ncbi gi num :

74315354

ncbi acc num :

NP_542437

ncbi gb acc num :

NM_080706.3

uniprot acc num :

Q8NER1

ncbi mol weight :

Predicted: 92 kDa

ncbi pathways :

Inflammatory Mediator Regulation Of TRP Channels Pathway (948277); Inflammatory Mediator Regulation Of TRP Channels Pathway (948307); Ion Channel Transport Pathway (187193); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Stimuli-sensing Channels Pathway (771568); TRP Channels Pathway (906028); Transmembrane Transport Of Small Molecules Pathway (106572); Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway (137967); Trk Receptor Signaling Mediated By The MAPK Pathway (138044)

ncbi summary :

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Protein type: Channel, cation; Membrane protein, multi-pass; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 17p13.2. Cellular Component: postsynaptic membrane; integral to plasma membrane; integral to membrane; plasma membrane; cell junction; intrinsic to plasma membrane. Molecular Function: calmodulin binding; transmembrane receptor activity; excitatory extracellular ligand-gated ion channel activity; calcium-release channel activity; calcium channel activity; phosphoprotein binding; ATP binding. Biological Process: cell surface receptor linked signal transduction; transport; chemosensory behavior; thermoception; transmembrane transport

size1 :

0.1 mg

price1 :

375 USD

more info or order :

MyBioSource product webpage