This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
PD-1 Recombinant Protein
catalog :
MBS153298
quantity :
0.05 mg
price :
250 USD
product information
catalog number :
MBS153298
products type :
Recombinant Protein
products full name :
PD-1 Recombinant Protein
products short name :
PD-1
products name syn :
PD-1 Recombinant Protein: PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death 1
other names :
programmed cell death 1; Programmed cell death protein 1; programmed cell death protein 1; mPD-1; protein PD-1; programmed cell death 1; CD_antigen: CD279
products gene name :
PDCD1
other gene names :
Pdcd1; PDCD1; PD-1; Pdc1; Ly101; PD1; Protein PD-1; hPD-1
uniprot entry name :
PDCD1_HUMAN
sequence length :
288
sequence :
aa 22 - 170
purity :
~95%
form :
Liquid
storage stability :
Store in working aliquots at -70 degree C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
tested application :
ELISA (EIA), Western Blot (WB), MS
app notes :
This recombinant protein can be used for WB, ELISA, MS and neutralization assays. For research use only.
other info1 :
Species: Mouse. Source: E Coli. Buffer: 1X PBS containing 0.1% SDS. Fusion Tag: Fusion Partner: C-terminal His-tag
products description :
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC) (1). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC (2). PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens (3). Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases (4).
ncbi gi num :
148707975
ncbi acc num :
EDL39922
uniprot acc num :
Q15116
ncbi mol weight :
19 kDa (Calculated)
ncbi pathways :
Adaptive Immune System Pathway 1110669!!Cell Adhesion Molecules (CAMs) Pathway 83266!!Cell Adhesion Molecules (CAMs) Pathway 480!!Costimulation By The CD28 Family Pathway 1110675!!Immune System Pathway 1110668!!PD-1 Signaling Pathway 1110680!!T Cell Receptor Signaling Pathway 83277!!T Cell Receptor Signaling Pathway 491
size :
0.05 mg
price :
250 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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