catalog number :
MBS153141
products type :
Blocking Peptide
products full name :
IFITM1 Peptide
products short name :
IFITM1
products name syn :
9-27; CD225; IFI17; LEU13; DSPA2a; Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; interferon induced transmembrane protein 1 (9-27)
other names :
interferon-induced transmembrane protein 1; Interferon-induced transmembrane protein 1; interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27; interferon induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD_antigen: CD225
products gene name :
IFITM1
other gene names :
IFITM1; IFITM1; 9-27; CD225; IFI17; LEU13; DSPA2a; CD225; IFI17; DSPA2a
uniprot entry name :
IFM1_HUMAN
concentration :
200 ug/mL
storage stability :
Store IFITM1 peptide at -20 degree C, stable for one year.
tested application :
Blocking (BL)
app notes :
IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 14 amino acids near the carboxy terminus of human IFITM1.
ncbi gb acc num :
NM_003641.3
ncbi mol weight :
13,964 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); Cytokine Signaling In Immune System Pathway (366171); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413); Interferon Signaling Pathway (187103); Interferon Alpha/beta Signaling Pathway (187104)
uniprot summary :
IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Belongs to the CD225/Dispanin family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell cycle regulation. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: membrane; integral to membrane; plasma membrane. Molecular Function: protein binding; receptor signaling protein activity. Biological Process: negative regulation of cell proliferation; positive regulation of osteoblast differentiation; ossification; regulation of immune response; cell surface receptor linked signal transduction; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus; cytokine and chemokine mediated signaling pathway; defense response to virus; negative regulation of cell migration