catalog number :
MBS152909
products type :
Blocking Peptide
products full name :
ABIN3 Peptide
products short name :
ABIN3
products name syn :
LIND; ABIN-3; ABIN3; LIND; TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; TNFAIP3 interacting protein 3
other names :
TNFAIP3-interacting protein 3 isoform 1; TNFAIP3-interacting protein 3; TNFAIP3-interacting protein 3; TNIP3 beta; ABIN-3 beta; Listeria induced; listeria-induced gene protein; TNFAIP3-interacting protein 3 beta; A20-binding inhibitor of NF-kappa-B activation 3; TNFAIP3 interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; Listeria-induced gene protein
products gene name :
TNIP3
other gene names :
TNIP3; TNIP3; LIND; ABIN-3; ABIN-3
uniprot entry name :
TNIP3_HUMAN
concentration :
200 ug/mL
storage stability :
Store ABIN3 peptide at -20 degree C, stable for one year.
tested application :
Blocking (BL)
app notes :
ABIN3 peptide is used for blocking the activity of ABIN3 antibody.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 17 amino acids near the carboxy terminus of human ABIN3.
ncbi gb acc num :
NM_024873.5
ncbi mol weight :
44,886 Da
uniprot summary :
TNIP3: Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 4q27. Molecular Function: polyubiquitin binding. Biological Process: MyD88-independent toll-like receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; inflammatory response; toll-like receptor 4 signaling pathway