product summary
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company name :
MyBioSource
product type :
protein
product name :
TET3 Peptide
catalog :
MBS152112
quantity :
0.05 mg
price :
135 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS152112
products type :
Blocking Peptide
products full name :
TET3 Peptide
products short name :
TET3
products name syn :
hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; TET methylcytosine dioxygenase 3
other names :
Methylcytosine dioxygenase TET3; methylcytosine dioxygenase TET3; tet methylcytosine dioxygenase 3
products gene name :
TET3
other gene names :
TET3; TET3; hCG_40738; KIAA0401
uniprot entry name :
TET3_HUMAN
sequence length :
727
form :
Liquid
concentration :
200 ug/mL
storage stability :
Store TET3 peptide at -20 degree C, stable for one year.
tested application :
Blocking (BL)
app notes :
TET3 peptide is used for blocking the activity of TET3 antibody.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 17 amino acid peptide near the carboxy terminus of human TET3.
ncbi gi num :
149944516
ncbi acc num :
NP_659430
ncbi gb acc num :
NM_144993.1
uniprot acc num :
O43151
ncbi mol weight :
77,471 Da
ncbi pathways :
Epigenetic Regulation Of Gene Expression Pathway (1127671); Gene Expression Pathway (105937); TET1,2,3 And TDG Demethylate DNA Pathway (1127673)
ncbi summary :
Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010]
uniprot summary :
TET3: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming in the zygote following fertilization. Conversion into 5hmC initiates a process leading to cytosine demethylation through deamination into 5-hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in DNA demethylation in the paternal pronucleus by mediating conversion of 5mC into 5hmC. Does not mediate DNA demethylation of maternal pronucleus because of the presence of DPPA3/PGC7 on maternal chromatin that prevents TET3-binding to chromatin. Belongs to the TET family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.14.11.n2; Oxidoreductase. Chromosomal Location of Human Ortholog: 2p13.1. Cellular Component: male pronucleus; cytoplasm; female pronucleus. Molecular Function: protein binding; DNA binding; metal ion binding. Biological Process: protein amino acid O-linked glycosylation; gene expression; positive regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic
size1 :
0.05 mg
price1 :
135 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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