product summary
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company name :
MyBioSource
product type :
protein
product name :
KAI1 Peptide
catalog :
MBS151902
quantity :
0.05 mg
price :
135 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS151902
products type :
Blocking Peptide
products full name :
KAI1 Peptide
products short name :
KAI1
products name syn :
R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82 antigen; C33 antigen; Tspan-27; CD82 molecule
other names :
CD82 antigen isoform 1; CD82 antigen; CD82 antigen; tspan-27; C33 antigen; tetraspanin-27; inducible membrane protein R2; metastasis suppressor Kangai-1; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); CD82 molecule; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; CD_antigen: CD82
products gene name :
CD82
other gene names :
CD82; CD82; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; KAI1; SAR2; ST6; TSPAN27; Tspan-27
uniprot entry name :
CD82_HUMAN
sequence length :
267
form :
Liquid
concentration :
200 ug/mL
storage stability :
Store KAI1 peptide at -20 degree C, stable for one year.
tested application :
Blocking (BL)
app notes :
KAI1 peptide is used for blocking the activity of KAI1 antibody.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 15 amino acids near the carboxy terminus of human KAI1
ncbi gi num :
4504813
ncbi acc num :
NP_002222
ncbi gb acc num :
NM_002231.3
uniprot acc num :
P27701
ncbi mol weight :
26,818 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); Integrated Pancreatic Cancer Pathway (711360); P53 Signaling Pathway (83055); P53 Signaling Pathway (465)
ncbi summary :
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
CD82: a widespread transmembrane protein of the tetraspanin family. A metastasis-suppressor whose decreased expression may be involved in malignant progression. Suppresses tumor metastasis of many cancers including cancers of the prostate, bladder, colon, cervix, liver, and lung (NSCLC). It is a target of estrogen receptor-mediated gene repression and is downregulated in primary human breast cancer. May be a prognostic marker for lung cancer and tumor metastatic potential. Interacts with cell surface proteins including integrins, cadherins, CD4, CD8, IGSF8. Modulates EGFR signaling. May suppress invasion by inhibiting integrin-dependent crosstalk with c-Met receptor and Src kinases. Its regulation of c-Met signaling apparently affects cancer cell migration. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 11p11.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Disease: Prostate Cancer
size1 :
0.05 mg
price1 :
135 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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