catalog number :
MBS151794
products type :
Blocking Peptide
products full name :
CAPS1 Peptide
products short name :
CAPS1
products name syn :
CAPS; CAPS1; CADPS1; CAPS; KIAA1121; Calcium-dependent secretion activator 1; Calcium-dependent activator protein for secretion 1; CAPS-1; Ca++-dependent secretion activator
other names :
calcium-dependent secretion activator 1 isoform 2; Calcium-dependent secretion activator 1; calcium-dependent secretion activator 1; CAPS-1; Ca2+-dependent secretion activator; Ca2+-regulated cytoskeletal protein; Ca2+-dependent activator protein for secretion; calcium-dependent activator protein for secretion 1; Ca++-dependent secretion activator; Calcium-dependent activator protein for secretion 1; CAPS-1
products gene name :
CADPS
other gene names :
CADPS; CADPS; CAPS; CAPS1; CADPS1; CAPS; CAPS1; KIAA1121; CAPS-1
uniprot entry name :
CAPS1_HUMAN
concentration :
200 ug/mL
storage stability :
Store CAPS1 peptide at -20 degree C, stable for one year.
tested application :
Blocking (BL)
app notes :
CAPS1 peptide is used for blocking the activity of CAPS1 antibody.
other info1 :
Species: Human. Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Location: 20 amino acids near the carboxy terminus of human CAPS1.
ncbi gb acc num :
NM_183394.2
ncbi mol weight :
50,236 Da
ncbi summary :
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
uniprot summary :
CADPS: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 3p14.2. Cellular Component: cytoplasmic vesicle membrane; synapse; cytosol; cell junction. Molecular Function: protein binding; metal ion binding; lipid binding; protein kinase binding. Biological Process: catecholamine secretion; protein transport; exocytosis; vesicle organization and biogenesis; synaptic vesicle priming