antibody

ZIP14 Antibody

MBS151580

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

ZIP14 Antibody

ZIP14

ZIP14; NET34; ZIP14; cig19; LZT-Hs4; KIAA0062; Zinc transporter ZIP14; LIV-1 subfamily of ZIP zinc transporter 4; solute carrier family 39 (zinc transporter), member 14

zinc transporter ZIP14 isoform a; Zinc transporter ZIP14; zinc transporter ZIP14; ZIP-14; Zrt-, Irt-like protein 14; zrt- and Irt-like protein 14; solute carrier family 39 member 14; LIV-1 subfamily of ZIP zinc transporter 4; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Solute carrier family 39 member 14; Zrt- and Irt-like protein 14; ZIP-14

Slc39a14

SLC39A14; SLC39A14; NET34; ZIP14; cig19; LZT-Hs4; KIAA0062; ZIP14; LZT-Hs4; ZIP-14

S39AE_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

492

At least three isoforms of ZIP14 are known to exist; this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.

ZIP14 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

ZIP14 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

ZIP14 antibody can be used for detection of ZIP14 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: ZIP14 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP14. Buffer: ZIP14 Antibody is supplied in PBS containing 0.02% sodium azide.

ZIP14 Antibody: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

205830424

NP_001128625

NM_001135153.1

Q15043

Predicted: 54 kDa. Observed: 52 kDa

Metal Ion SLC Transporters Pathway 161066!!SLC-mediated Transmembrane Transport Pathway 119558!!Transmembrane Transport Of Small Molecules Pathway 106572!!Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway 119571!!Zinc Influx Into Cells By The SLC39 Gene Family Pathway 161069!!Zinc Transporters Pathway 161067

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

0.1 mg

345 USD