antibody

ZEB1 Antibody

MBS151570

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunocytochemistry, enzyme immunoassay

Antibody

ZEB1 Antibody

ZEB1

ZEB1; BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1; Zinc finger E-box-binding homeobox 1; NIL-2-A zinc finger protein; TCF-8; zinc finger E-box binding homeobox 1

Zinc finger E-box-binding homeobox 1; zinc finger E-box-binding homeobox 1; negative regulator of IL2; delta-crystallin enhancer binding factor 1; posterior polymorphous corneal dystrophy 3; zinc finger homeodomain enhancer-binding protein; transcription factor 8 (represses interleukin 2 expression); zinc finger E-box binding homeobox 1; NIL-2-A zinc finger protein; Negative regulator of IL2; Transcription factor 8; TCF-8

ZEB1

ZEB1; ZEB1; BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1; AREB6; TCF8; TCF-8

ZEB1_HUMAN

Polyclonal

IgG

Rabbit

Human

1,108

Multiple isoforms of ZEB1 are known to exist.

ZEB1 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

ZEB1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

ZEB1 antibody can be used for detection of ZEB1 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: ZEB1 antibody was raised against a 15 amino acid synthetic peptide near the center of human ZEB1. Buffer: ZEB1 Antibody is supplied in PBS containing 0.02% sodium azide.

ZEB1 Antibody: ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.

55957123

NP_110378

P37275

Predicted: 124 kDa. Observed: 130 kDa

Hypertrophy Model Pathway 198828!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!TGF-beta Receptor Signaling Pathway 198774!!Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987

This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]

0.1 mg

345 USD