product summary
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company name :
MyBioSource
product type :
antibody
product name :
IL-31 Antibody
catalog :
MBS151553
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, enzyme immunoassay, immunohistochemistry - paraffin section
more info or order :
image
image 1 :
Immunohistochemistry of IL-31 in rat skeletal muscle tissue with IL-31 antibody at 10 g/mL.
product information
catalog number :
MBS151553
products type :
Antibody
products full name :
IL-31 Antibody
products short name :
[IL-31]
products name syn :
[IL-31; 1700013B14Rik; Interleukin-31; IL-31; interleukin 31]
other names :
[interleukin 31; Interleukin-31; interleukin-31; IL-31; interleukin 31]
products gene name :
[Il31]
other gene names :
[Il31; Il31; 1700013B14Rik; IL-31]
uniprot entry name :
IL31_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
163
purity :
IL-31 Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
IL-31 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry-paraffin (IHC-P)
app notes :
IL-31 antibody can be used for the detection of IL-31 by Western blot at 2.5 - 10 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Conjugate: Unconjugated. Immunogen: IL-31 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31. The immunogen is located within amino acids 30 - 80 of IL-31. Buffer: IL-31 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
IL-31 Antibody: Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
ncbi gi num :
46241139
ncbi acc num :
AAS82846
uniprot acc num :
Q6EAL8
ncbi mol weight :
18,120 Da
uniprot summary :
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. Protein type: Secreted; Secreted, signal peptide; Cytokine. Cellular Component: extracellular space; extracellular region. Molecular Function: cytokine activity. Biological Process: immune system process
size1 :
0.1 mg
price1 :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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