catalog number :
MBS151512
products full name :
FCHO2 Antibody
products short name :
FCHO2
products name syn :
FCHO2; FCH domain only protein 2; FCH domain only 2
other names :
FCH domain only protein 2 isoform a; FCH domain only protein 2; FCH domain only protein 2; FCH domain only 2
products gene name :
FCHO2
other gene names :
FCHO2; FCHO2
uniprot entry name :
FCHO2_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
FCHO2 antibody is predicted to not cross-react with other FCHO protein family members. At least the isoforms of FCHO2 are known to exist; this antibody will detect only the two longest isoforms.
purity :
FCHO2 Antibody is affinity chromatography purified via peptide column.
storage stability :
FCHO2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
FCHO2 antibody can be used for detection of FCHO2 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 2.5 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: FCHO2 antibody was raised against a 15 amino acid synthetic peptide near the center of human FCHO2. Buffer: FCHO2 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
FCHO2 Antibody: FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.
ncbi gb acc num :
NM_138782.2
ncbi mol weight :
85,146 Da