APOBEC3G Antibody | MyBioSource MBS151507 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

APOBEC3G Antibody

catalog :

MBS151507

quantity :

0.1 mg

price :

345 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS151507

products type :

Antibody

products full name :

APOBEC3G Antibody

products short name :

APOBEC3G

products name syn :

APOBEC3G; A3G; ARCD; ARP9; ARP-9; CEM15; CEM-15; MDS019; bK150C2.7; dJ494G10.1APOBEC-related cytidine deaminase; APOBEC-related protein; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G

other names :

DNA dC- dU-editing enzyme APOBEC-3G; DNA dC->dU-editing enzyme APOBEC-3G; DNA dC- dU-editing enzyme APOBEC-3G; deoxycytidine deaminase; APOBEC-related protein 9; DNA dC- dU editing enzyme; phorbolin-like protein MDS019; APOBEC-related cytidine deaminase; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B editing enzyme catalytic polypeptide-like 3G; apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3G; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; APOBEC-related cytidine deaminase; APOBEC-related protein; ARCD; APOBEC-related protein 9; ARP-9; CEM-15; CEM15; Deoxycytidine deaminase; A3G

products gene name :

APOBEC3G

other gene names :

APOBEC3G; APOBEC3G; A3G; ARCD; ARP9; ARP-9; CEM15; CEM-15; MDS019; bK150C2.7; dJ494G10.1; APOBEC-related protein; ARCD; ARP-9; CEM15; A3G

uniprot entry name :

ABC3G_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

384

specificity :

APOBEC3G antibody will also detect the APOBEC3F isoform.

purity :

APOBEC3G Antibody is affinity chromatography purified via peptide column.

form :

Liquid

concentration :

1 mg/mL

storage stability :

APOBEC3G antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

APOBEC3G antibody can be used for detection of APOBEC3G by Western blot at 5 mug/mL. Antibody can also be used for immunohistochemistry starting at 1 mug/mL.

other info1 :

Conjugate: Unconjugated. Immunogen: APOBEC3G antibody was raised against a synthetic peptide corresponding to 15 amino acids near the amino-terminus of human APOBEC3G. Buffer: APOBEC3G Antibody is supplied in PBS containing 0.02% sodium azide.

products description :

APOBEC3G Antibody: The Apoliprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection as at least two isoforms, APOBEC3G and to a lesser extent APOBEC3F, can be incorporated HIV-1 virions and induce hypermutation in the newly synthesized viral DNA and thus destabilize the viral genome. This innate mechanism of retroviral resistance is counteracted by the HIV-1 Vif protein by inducing the ubiquitization and degradation of APOBEC3G; a single amino acid substitution (D128K) blocks APOBEC3G depletion without affecting its inhibitory activity.

ncbi gi num :

13399304

ncbi acc num :

NP_068594

ncbi gb acc num :

NM_021822.3

uniprot acc num :

Q9HC16

ncbi mol weight :

9,386 Da

ncbi pathways :

APOBEC3G Mediated Resistance To HIV-1 Infection Pathway 106016!!Disease Pathway 530764!!HIV Infection Pathway 105983!!Host Interactions Of HIV Factors Pathway 106010!!Integrated Breast Cancer Pathway 219801!!Vif-mediated Degradation Of APOBEC3G Pathway 106017

ncbi summary :

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

345 USD

more info or order :

MyBioSource product webpage