catalog number :
MBS151504
products full name :
YBX2 Antibody
products short name :
YBX2
products name syn :
YBX2; DBPC; MSY2; CSDA3; CONTRIN; Y-box-binding protein 2; Contrin; Dbpc; Y box binding protein 2
other names :
Y-box-binding protein 2; Y-box-binding protein 2; Y-box-binding protein 2; MSY2 homolog; DNA-binding protein C; germ cell specific Y-box binding protein; germ cell-specific Y-box-binding protein; Y box binding protein 2; Contrin; DNA-binding protein C; Dbpc; Germ cell-specific Y-box-binding protein; MSY2 homolog
products gene name :
YBX2
other gene names :
YBX2; YBX2; DBPC; MSY2; CSDA3; CONTRIN; CSDA3; MSY2; Dbpc
uniprot entry name :
YBOX2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
YBX2 Antibody is affinity chromatography purified via peptide column.
storage stability :
YBX2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
YBX2 antibody can be used for detection of YBX2 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: YBX2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy end of human YBX2. Buffer: YBX2 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
YBX2 Antibody: Germ cell specific Y-box binding protein (YBX2), a germ-cell-specific member of the Y-box family of DNA-/RNA-binding proteins, is a major constituent of messenger ribonucleoprotein particles (mRNPs) and involved in the regulation of the stability and/or translation of germ cell mRNAs. It is proposed to function as a coactivator of transcription in the nucleus and to stabilize and store maternal and paternal mRNAs in the cytoplasm. YBX2 binds to the Y-box consensus promoter element and is expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Recent studies show that deletion of YBX2 leads to the disruption of both spermatogenesis and oogenesis.
ncbi gb acc num :
NM_015982.3
ncbi mol weight :
38,518 Da
ncbi summary :
This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]