product summary
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company name :
MyBioSource
product type :
antibody
product name :
TMEM16A Antibody
catalog :
MBS151482
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS151482
products type :
Antibody
products full name :
TMEM16A Antibody
products short name :
TMEM16A
products name syn :
TMEM16A; DOG1; TAOS2; ORAOV2; TMEM16A; DOG1; Anoctamin-1; Discovered on gastrointestinal stromal tumors protein 1; anoctamin 1, calcium activated chloride channel
other names :
anoctamin-1; Anoctamin-1; anoctamin-1; Ca2+-activated Cl- channel; oral cancer overexpressed 2; tumor-amplified and overexpressed sequence 2; discovered on gastrointestinal stromal tumors protein 1; transmembrane protein 16A (eight membrane-spanning domains); anoctamin 1, calcium activated chloride channel; Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2
products gene name :
ANO1
other gene names :
ANO1; ANO1; DOG1; TAOS2; ORAOV2; TMEM16A; DOG1; ORAOV2; TAOS2; TMEM16A
uniprot entry name :
ANO1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
986
purity :
TMEM16A Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
TMEM16A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
TMEM16A antibody can be used for detection of TMEM16A by Western blot at 1 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: TMEM16A antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human TMEM16A. Buffer: TMEM16A Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
TMEM16A Antibody: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16A is expressed in epithelial cells of the kidney and lung, pancreas, and sensory neurons and its mRNA is seen in foregut, airway epithelia, and tracheal smooth muscle; mice lacking TMEM16A fail to survive past ten days and show aerophagia and little weight gain. TMEM16A is also overexpressed or amplified in multiple cancers associated with poor survival such as oral cancers and gastrointestinal stromal tumors, suggesting the development of CaCC modulators may be a viable therapeutic strategy.
ncbi gi num :
194306539
ncbi acc num :
NP_060513
ncbi gb acc num :
NM_018043.5
uniprot acc num :
Q5XXA6
ncbi mol weight :
74,369 Da
ncbi pathways :
Ion Channel Transport Pathway 187193!!Orphan Transporters Pathway 1127546!!Stimuli-sensing Channels Pathway 771568!!Transmembrane Transport Of Small Molecules Pathway 106572
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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