product summary
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company name :
MyBioSource
product type :
antibody
product name :
PERP Antibody
catalog :
MBS151420
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS151420
products type :
Antibody
products full name :
PERP Antibody
products short name :
PERP
products name syn :
PERP; THW; KCP1; PIGPC1; KRTCAP1; 1110017A08Rik; Krtcap1; p53 apoptosis effector related to PMP-22; Keratinocyte-associated protein 1; KCP-1; PERP, TP53 apoptosis effector
other names :
p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP-22; KCP-1; p53 apoptosis-associated target; keratinocyte-associated protein 1; p53 apoptosis effector related to Pmp22; PERP, TP53 apoptosis effector; Keratinocyte-associated protein 1; KCP-1
products gene name :
Perp
other gene names :
Perp; Perp; THW; KCP1; PIGPC1; KRTCAP1; 1110017A08Rik; Krtcap1; KCP-1
uniprot entry name :
PERP_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
193
purity :
PERP Antibody is Antibody is DEAE purified.
form :
Liquid
storage stability :
PERP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
app notes :
PERP antibody can be used for detection of PERP by Western blot at 1 mug/mL. A 21 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: PERP antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids. Buffer: PERP Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
PERP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
ncbi gi num :
11528520
ncbi acc num :
NP_071315
ncbi gb acc num :
NM_022032.4
uniprot acc num :
Q9JK95
ncbi mol weight :
21 kDa
ncbi pathways :
PluriNetWork Pathway (198307); P53 Signaling Pathway (83252); P53 Signaling Pathway (465)
uniprot summary :
PERP: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Belongs to the TMEM47 family. Protein type: Membrane protein, multi-pass; Mitochondrial; Cell adhesion; Membrane protein, integral. Cellular Component: Golgi apparatus; mitochondrion; membrane; integral to plasma membrane; integral to membrane; plasma membrane; cell junction. Biological Process: heterotypic cell-cell adhesion; apoptosis; positive regulation of proteolysis; cell adhesion
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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