antibody

JMJD1A Antibody

MBS151357

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

JMJD1A Antibody

JMJD1A

JMJD1A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A; KIAA0742; TSGA; Lysine-specific demethylase 3A; JmjC domain-containing histone demethylation protein 2A; lysine (K)-specific demethylase 3A

lysine-specific demethylase 3A; Lysine-specific demethylase 3A; lysine-specific demethylase 3A; testis-specific protein A; jumonji domain containing 1; jumonji domain containing 1A; jumonji domain-containing protein 1A; jumonji C domain-containing histone demethylase 2A; jmjC domain-containing histone demethylation protein 2A; lysine (K)-specific demethylase 3A; JmjC domain-containing histone demethylation protein 2A; Jumonji domain-containing protein 1A

KDM3A

KDM3A; KDM3A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A; JHDM2A; JMJD1; JMJD1A; KIAA0742; TSGA

KDM3A_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

1321

This antibody will not cross-react with JMJD1B or JMJD1C.

JMJD1A Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

JMJD1A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

JMJD1A antibody can be used for detection of JMJD1A by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: JMJD1A antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human JMJD1A. Buffer: JMJD1A Antibody is supplied in PBS containing 0.02% sodium azide.

JMJD1A Antibody: The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.

20357522

NP_060903

NM_018433.5

Q9Y4C1

147,341 Da

Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!Coregulation Of Androgen Receptor Activity Pathway 138085!!HDMs Demethylate Histones Pathway 1127685

This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

0.1 mg

345 USD