catalog number :
MBS151310
products full name :
ATP11A Antibody
products short name :
ATP11A
products name syn :
ATP11A; ATPIH; ATPIS; ATPIH; KIAA1021; Probable phospholipid-transporting ATPase IH; ATPase IS; ATPase, class VI, type 11A
other names :
probable phospholipid-transporting ATPase IH isoform b; Probable phospholipid-transporting ATPase IH; probable phospholipid-transporting ATPase IH; phospholipid-translocating ATPase; potential phospholipid-transporting ATPase IH; P4-ATPase flippase complex alpha subunit ATP11A; ATPase, class VI, type 11A; ATPase IS; ATPase class VI type 11A; P4-ATPase flippase complex alpha subunit ATP11A
products gene name :
ATP11A
other gene names :
ATP11A; ATP11A; ATPIH; ATPIS; ATPIH; ATPIS; KIAA1021
uniprot entry name :
AT11A_HUMAN
reactivity :
Human, Mouse, Rat
purity :
ATP11A Antibody is affinity chromatography purified via peptide column.
storage stability :
ATP11A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
app notes :
ATP11A antibody can be used for detection of ATP11A by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: ATP11A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A. Buffer: ATP11A Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
ATP11A Antibody: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
ncbi gb acc num :
NM_032189.3
ncbi mol weight :
129,756 Da
ncbi pathways :
Ion Channel Transport Pathway 187193!!Ion Transport By P-type ATPases Pathway 187194!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]