product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
ECRG4 Antibody
catalog :
MBS151199
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS151199
products type :
Antibody
products full name :
ECRG4 Antibody
products short name :
ECRG4
products name syn :
ECRG4; ECRG4; ECRG4; UNQ761/PRO1508; Augurin; Esophageal cancer-related gene 4 protein; chromosome 2 open reading frame 40
other names :
augurin; Augurin; augurin; esophageal cancer related gene 4 protein; esophageal cancer-related gene 4 protein; chromosome 2 open reading frame 40; Esophageal cancer-related gene 4 protein
products gene name :
C2orf40
other gene names :
C2orf40; C2orf40; ECRG4; ECRG4
uniprot entry name :
AUGN_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
148
specificity :
ECRG4 antibody is predicted to not cross-react with other ECRG family members.
purity :
ECRG4 Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
ECRG4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
app notes :
ECRG4 antibody can be used for detection of ECRG4 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: ECRG4 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ECRG4. Buffer: ECRG4 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
ECRG4 Antibody: The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.
ncbi gi num :
14165276
ncbi acc num :
AAI09386
ncbi gb acc num :
NM_032411.2
uniprot acc num :
Q9H1Z8
ncbi mol weight :
17,183 Da
uniprot summary :
C2orf40: Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. Belongs to the augurin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2q12.2. Cellular Component: extracellular space; transport vesicle. Biological Process: cyclin catabolic process
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!