catalog number :
MBS151124
products full name :
Slc22A17 Antibody
products short name :
Slc22A17
products name syn :
Slc22A17; BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3; BOCT; Solute carrier family 22 member 17; 24p3 receptor; solute carrier family 22, member 17
other names :
Solute carrier family 22 member 17; Solute carrier family 22 member 17; solute carrier family 22 member 17; 24p3 receptor; NGAL receptor; lipocalin-2 receptor; brain-type organic cation transporter; potent brain type organic ion transporter; neutrophil gelatinase-associated lipocalin receptor; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22, member 17; 24p3 receptor; 24p3R; Brain-type organic cation transporter; Lipocalin-2 receptor; Neutrophil gelatinase-associated lipocalin receptor; NgalR
products gene name :
SLC22A17
other gene names :
SLC22A17; SLC22A17; BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3; BOCT; BOIT; 24p3R; NgalR
uniprot entry name :
S22AH_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Slc22A17 Antibody is affinity chromatography purified via peptide column.
storage stability :
Slc22A17 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
Slc22A17 antibody can be used for detection of Slc22A17 by Western blot at 1 mug/mL. Antibody can also be used for immunoflourescence starting at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: Slc22A17 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17. Buffer: Slc22A17 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
Slc22A17 Antibody: The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.
ncbi mol weight :
Predicted: 59 kDa. Observed: 61 kDa
ncbi pathways :
Iron Uptake And Transport Pathway 187191!!Orphan Transporters Pathway 1127546!!Transmembrane Transport Of Small Molecules Pathway 106572