catalog number :
MBS151080
products full name :
SGSM2 Antibody
products short name :
SGSM2
products name syn :
SGSM2; RUTBC1; KIAA0397; RUTBC1; Small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2
other names :
small G protein signaling modulator 2 isoform 1; Small G protein signaling modulator 2; small G protein signaling modulator 2; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2 protein; small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1
products gene name :
SGSM2
other gene names :
SGSM2; SGSM2; RUTBC1; KIAA0397; RUTBC1
uniprot entry name :
SGSM2_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.
purity :
SGSM2 Antibody is affinity chromatography purified via peptide column.
storage stability :
SGSM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2. Buffer: SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
ncbi gb acc num :
NM_014853.2
ncbi mol weight :
116 kDa
uniprot summary :
SGSM2: Belongs to the RUTBC family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: G protein regulator, misc. Chromosomal Location of Human Ortholog: 17p13.3. Molecular Function: Rab GTPase binding