catalog number :
MBS151061
products full name :
CTRP4 Antibody
products short name :
[CTRP4]
products name syn :
[CTRP4; CTRP4; ZACRP4; CTRP4; Complement C1q tumor necrosis factor-related protein 4; C1q and tumor necrosis factor related protein 4]
other names :
[C1q and tumor necrosis factor related protein 4; Complement C1q tumor necrosis factor-related protein 4; complement C1q tumor necrosis factor-related protein 4; complement-c1q tumor necrosis factor-related protein 4; C1q and tumor necrosis factor related protein 4]
products gene name :
[C1QTNF4]
other gene names :
[C1QTNF4; C1QTNF4; CTRP4; ZACRP4; CTRP4]
uniprot entry name :
C1QT4_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
purity :
CTRP4 Antibody is affinity chromatography purified via peptide column.
storage stability :
CTRP4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry Paraffin (IHC-P), Immunofluorescence (IF)
app notes :
CTRP4 antibody can be used for the detection of CTRP4 by Western blot at 1 - 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL. Optimal dilutions for each application to be determined by the researcher.
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Conjugate: Unconjugated. Immunogen: CTRP4 antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP4. The immunogen is located within amino acids 90-140 of CTRP4. Buffer: CTRP4 Antibody is supplied in PBS containing 0.02% sodium azide.
other info2 :
Positive Control: 1. MBS151758- Rat Brain Tissue Lysate. 2. MBS151732- Human Brain Tissue Lysate. 3. MBS154323- Human Brain Tissue Slide
products description :
CTRP4 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.
ncbi mol weight :
35,256 Da
uniprot summary :
C1QTNF4: May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production. Up-regulated by IL6. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11q11. Cellular Component: extracellular space. Molecular Function: cytokine activity