product summary
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company name :
MyBioSource
product type :
antibody
product name :
TRIM71 Antibody
catalog :
MBS151027
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS151027
products type :
Antibody
products full name :
TRIM71 Antibody
products short name :
TRIM71
products name syn :
TRIM71; LIN41; LIN-41; LIN41; E3 ubiquitin-protein ligase TRIM71; Protein lin-41 homolog; tripartite motif-containing 71
other names :
E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase TRIM71; protein lin-41 homolog; abnormal cell LINeage LIN-41; homolog of C. elegans Lin-41; tripartite motif-containing 71; tripartite motif-containing protein 71; tripartite motif containing 71, E3 ubiquitin protein ligase; Protein lin-41 homolog; Tripartite motif-containing protein 71
products gene name :
TRIM71
other gene names :
TRIM71; TRIM71; LIN41; LIN-41; LIN41
uniprot entry name :
LIN41_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
868
purity :
TRIM71 Antibody is affinity chromatography purified via peptide column.
form :
Liquid
concentration :
1 mg/mL
storage stability :
TRIM71 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
TRIM71 antibody can be used for detection of TRIM71 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
other info1 :
Conjugate: Unconjugated. Immunogen: TRIM71 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TRIM71. Buffer: TRIM71 Antibody is supplied in PBS containing 0.02% sodium azide.
products description :
TRIM71 Antibody: TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.
ncbi gi num :
84993742
ncbi acc num :
NP_001034200
ncbi gb acc num :
NM_001039111.1
uniprot acc num :
Q2Q1W2
ncbi mol weight :
93,385 Da
ncbi pathways :
MicroRNAs In Cancer Pathway (852705); MicroRNAs In Cancer Pathway (852928)
uniprot summary :
TRIM71: May be involved in controlling the timing of organ formation during development. Belongs to the TRIM/RBCC family. Chromosomal Location of Human Ortholog: 3p22.3. Molecular Function: miRNA binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity. Biological Process: neural tube development; protein autoubiquitination; fibroblast growth factor receptor signaling pathway; neural tube closure; miRNA-mediated gene silencing, negative regulation of translation; G1/S transition of mitotic cell cycle
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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