antibody

ZIP8 Antibody

MBS151012

0.1 mg

345 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

ZIP8 Antibody

ZIP8

ZIP8; ZIP8; PP3105; BIGM103; LZT-Hs6; ZIP8; Zinc transporter ZIP8; BCG-induced integral membrane protein in monocyte clone 103 protein; solute carrier family 39 (zinc transporter), member 8

zinc transporter ZIP8 isoform a; Zinc transporter ZIP8; zinc transporter ZIP8; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc transporter 6; BCG induced integral membrane protein BIGM103; solute carrier family 39 (metal ion transporter), member 8; BCG-induced integral membrane protein in monocyte clone 103 protein; solute carrier family 39 (zinc transporter), member 8; BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8

Slc39a8

SLC39A8; SLC39A8; ZIP8; PP3105; BIGM103; LZT-Hs6; BIGM103; ZIP8; LZT-Hs6; ZIP-8

S39A8_HUMAN

Polyclonal

IgG

Rabbit

Human

460

ZIP8 antibody is predicted to not cross-react with other ZIP family members.

ZIP8 Antibody is affinity chromatography purified via peptide column.

Liquid

1 mg/mL

ZIP8 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

ZIP8 antibody can be used for detection of ZIP8 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Conjugate: Unconjugated. Immunogen: ZIP8 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZIP8. Buffer: ZIP8 Antibody is supplied in PBS containing 0.02% sodium azide.

ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.

205830403

NP_071437

NM_001135146.1

Q9C0K1

48,089 Da

Metal Ion SLC Transporters Pathway 161066!!SLC-mediated Transmembrane Transport Pathway 119558!!Transmembrane Transport Of Small Molecules Pathway 106572!!Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway 119571!!Zinc Influx Into Cells By The SLC39 Gene Family Pathway 161069!!Zinc Transporters Pathway 161067

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]

0.1 mg

345 USD